The antiserum was produced against synthesized Acetyl-peptide derived from human FOXA1 around the Acetylation site of Lys265. AA range:231-280

This antibody detects endogenous levels of HNF-3α/β/γ only when acetylated at Human:K264/253/211, Mouse:K264/253/213, Rat:K264/252/213.This antibody does not recognize acetylated at other sites.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RQkRF

FOXA1/FOXA2/FOXA3

Hepatocyte nuclear factor 3-alpha/Hepatocyte nuclear factor 3-beta/Hepatocyte nuclear factor 3-gamma

FOXA1 ;
HNF3A ;
TCF3A ;
Hepatocyte nuclear factor 3-alpha ;
HNF-3-alpha ;
HNF-3A ;
Forkhead box protein A1 ;
Transcription factor 3A ;
TCF-3A ;
FOXA2 ;
HNF3B ;
TCF3B ;
Hepatocyte nuclear factor 3-beta ;
HNF-3-beta ;
HNF-3B ;
Forkhead box protein A2 ;
Transcription factor 3B ;
TCF-3B ;
FOXA3 ;
HNF3G ;
TCF3G ;
Hepatocyte nuclear factor 3-gamma ;
HNF-3-gamma ;
HNF-3G ;
Fork head-related protein FKH H3 ;
Forkhead box protein A3 ;
Transcription factor 3G ;
TCF-3G

This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. [provided by RefSeq, Jul 2008],

Function:Transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes.,online information:Hepatocyte nuclear factors entry,similarity:Contains 1 fork-head DNA-binding domain.,

Nucleus .