Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

CSF1

Macrophage colony-stimulating factor 1

CSF1 ;
Macrophage colony-stimulating factor 1 ;
CSF-1 ;
M-CSF ;
MCSF ;
Lanimostim

function:Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy.,PTM:Glycosylation and proteolytic cleavage yield different soluble forms. A high molecular weight soluble form is a proteoglycan containing chondroitin sulfate.,PTM:Isoform 1 is N- and O-glycosylated. Isoform 3 is N-glycosylated.,subunit:Homodimer or heterodimer; disulfide-linked.,

cell activation, tissue homeostasis, regulation of cell-matrix adhesion, positive regulation of cell-matrix adhesion,myeloid leukocyte activation, immune system development, leukocyte differentiation, myeloid leukocyte differentiation,regulation of myeloid leukocyte differentiation, positive regulation of myeloid leukocyte differentiation, reproductive developmental process, cell proliferation, positive regulation of cell proliferation, positive regulation of signal transduction, positive regulation of macromolecule metabolic process, positive regulation of gene expression, positive regulation of cell communication, regulation of foam cell differentiation, positive regulation of foam cell differentiation,regulation of cell-substrate adhesion, positive regulation of cell-substrate adhesion, regulation of phosphate metabolic process, hemopoiesis, myeloid cell differentiation, regulation of cell adhesion, macrophage differentiation,regulation of ossification, regulation of cell migration, positive regulation of cell migration, regulation of cellular protein metabolic process, positive regulation of cellular protein metabolic process, regulation of mononuclear cell proliferation, positive regulation of mononuclear cell proliferation, positive regulation of kinase activity, regulation of growth, regulation of locomotion, regulation of multicellular organism growth, positive regulation of locomotion,positive regulation of multicellular organism growth, monocyte activation, regulation of cell proliferation, regulation of phosphorylation, odontogenesis, regulation of odontogenesis, positive regulation of odontogenesis, regulation of odontogenesis of dentine-containing tooth, positive regulation of odontogenesis of dentine-containing tooth,homeostatic process, positive regulation of catalytic activity, regulation of kinase activity, positive regulation of molecular function, leukocyte activation, positive regulation of cell differentiation, regulation of myeloid cell differentiation, positive regulation of myeloid cell differentiation, regulation of macrophage differentiation, positive regulation of macrophage differentiation, regulation of monocyte differentiation, positive regulation of monocyte differentiation, regulation of osteoclast differentiation, positive regulation of osteoclast differentiation, positive regulation of cell adhesion, regulation of protein kinase activity, positive regulation of protein kinase activity, positive regulation of growth, regulation of Ras protein signal transduction, positive regulation of Ras protein signal transduction, hemopoietic or lymphoid organ development, multicellular organismal homeostasis, homeostasis of number of cells, homeostasis of number of cells within a tissue, regulation of small GTPase mediated signal transduction, positive regulation of small GTPase mediated signal transduction, positive regulation of developmental process, regulation of phosphorus metabolic process, positive regulation of multicellular organismal process, positive regulation of protein metabolic process, regulation of cell motion, positive regulation of cell motion, regulation of transferase activity, positive regulation of transferase activity, anatomical structure homeostasis, regulation of leukocyte proliferation, positive regulation of leukocyte proliferation,

Cell membrane ; Single-pass type I membrane protein .; [Processed macrophage colony-stimulating factor 1]: Secreted, extracellular space.