EPHB4 (Phospho Tyr987) Rabbit pAb
-YP1682
主要信息
Target
EPHB4 Phospho Tyr987
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
110kD (Observed)
Conjugate/Modification
Phospho
货号: YP1682
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of EPHB4 (Phospho-Tyr987) at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):PQy
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
实测条带
110kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human EPHB4 (Phospho-Tyr987)
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特异性:
This antibody detects endogenous levels of EPHB4 (Phospho-Tyr987) at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):PQy
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基因名称:
EPHB4 HTK MYK1 TYRO11
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蛋白名称:
EPHB4 (Phospho-Tyr987)
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别名:
Ephrin type-B receptor 4 ;
Hepatoma transmembrane kinase ;
Tyrosine-protein kinase TYRO11 ;
Hepatoma transmembrane kinase ;
Tyrosine-protein kinase TYRO11 ;
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背景:
Ephrin receptors and their ligands , the ephrins , mediate numerous developmental processes , particularly in the nervous system. Based on their structures and sequence relationships , ephrins are divided into the ephrin-A (EFNA) class , which are anchored to the membrane by a glycosylphosphatidylinositol linkage , and the ephrin-B (EFNB) class , which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. [provided by RefSeq , Jul 2008] ,
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功能:
Catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. ,Function:Receptor for members of the ephrin-B family. Binds to ephrin-B2. May have a role in events mediating differentiation and development. ,PTM:Autophosphorylated. ,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. ,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. ,similarity:Contains 1 protein kinase domain. ,similarity:Contains 1 SAM (sterile alpha motif) domain. ,similarity:Contains 2 fibronectin type-III domains. ,tissue specificity:Abundantly expressed in placenta and in a range of primary tissues and malignant cell lines. Expressed in fetal , but not adult , brain , and in primitive and myeloid , but not lymphoid , hematopoietic cells. ,
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细胞定位:
Cell membrane ; Single-pass type I membrane protein .
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研究领域:
>>Axon guidance
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文献引用（{{totalcount}}）
货号: YP1682
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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