Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

IL15

Interleukin-15

IL15 ;
Interleukin-15 ;
IL-15

function:Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL-15 requires interaction of IL-15 with components of IL-2R, including IL-2R beta and probably IL-2R gamma but not IL-2R alpha.,online information:Interleukin-15 entry,sequence caution:Man-made cDNA construct with a sequence coding for signal peptide increasing the secretion of the protein (substitution with a signal peptide derived from the mouse IgV kappa chain).,similarity:Belongs to the IL-15/IL-21 family.,subcellular location:IL15-S21AA is not secreted, but rather is stored intracellularly, appearing in the nucleus and cytoplasmic components.,tissue specificity:Most abundant in placenta and skeletal muscle. It is also detected in the heart, lung, liver and kidney. IL15-S21AA is preferentially expressed in tissues such as testis and thymus.,

cell activation, NK T cell proliferation, immune system development, leukocyte differentiation, positive regulation of immune system process, regulation of leukocyte activation, positive regulation of leukocyte activation, regulation of immune effector process, regulation of response to biotic stimulus, defense response, inflammatory response, immune response, cell-cell signaling, aging, cell proliferation, positive regulation of cell proliferation, negative regulation of cell proliferation, response to wounding, hemopoiesis, lymphocyte differentiation, T cell differentiation, mononuclear cell proliferation, regulation of mononuclear cell proliferation, positive regulation of mononuclear cell proliferation,extrathymic T cell differentiation, T cell proliferation, positive regulation of T cell proliferation, T cell activation,regulation of cell proliferation, regulation of T cell proliferation, regulation of multi-organism process, T cell selection,extrathymic T cell selection, leukocyte activation, regulation of T cell differentiation, regulation of lymphocyte differentiation, alpha-beta T cell activation, alpha-beta T cell proliferation, lymphocyte activation, lymphocyte proliferation, hemopoietic or lymphoid organ development, lymph node development, positive regulation of response to stimulus, regulation of smooth muscle cell proliferation, negative regulation of smooth muscle cell proliferation,regulation of lymphocyte proliferation, positive regulation of lymphocyte proliferation, regulation of defense response to virus, regulation of defense response to virus by host, positive regulation of immune response, regulation of T cell activation, regulation of cell activation, positive regulation of cell activation, positive regulation of T cell activation,regulation of lymphocyte activation, positive regulation of lymphocyte activation, leukocyte proliferation, regulation of leukocyte proliferation, positive regulation of leukocyte proliferation,

[Isoform IL15-S48AA]: Secreted.; [Isoform IL15-S21AA]: Cytoplasm. Nucleus. IL15-S21AA is not secreted, but rather is stored intracellularly, appearing in the nucleus and cytoplasmic components.

Most abundant in placenta and skeletal muscle. It is also detected in the heart, lung, liver and kidney. IL15-S21AA is preferentially expressed in tissues such as testis and thymus.