Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

IL1R1

Interleukin-1 receptor type 1

IL1R1 ;
IL1R ;
IL1RA ;
IL1RT1 ;
Interleukin-1 receptor type 1 ;
IL-1R-1 ;
IL-1RT-1 ;
IL-1RT1 ;
CD121 antigen-like family member A ;
Interleukin-1 receptor alpha ;
IL-1R-alpha ;
Interleukin-1 receptor type I ;
p80 ;
CD antigen CD121a

function:Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2.,similarity:Belongs to the interleukin-1 receptor family.,similarity:Contains 1 TIR domain.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Binds IL1RAP.,

defense response, immune response, cell surface receptor linked signal transduction, response to organic substance,cytokine-mediated signaling pathway, response to cytokine stimulus, innate immune response, interleukin-1-mediated signaling pathway, response to interleukin-1,

Membrane ; Single-pass type I membrane protein . Cell membrane . Secreted .

Expressed in T-helper cell subsets. Preferentially expressed in T-helper 1 (Th1) cells.