Caveolin 2 (Phospho Ser23) Rabbit pAb
-YP1843
主要信息
Target
Caveolin-2 Phospho Ser23
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IHC, WB
MW
26kD (Observed)
Conjugate/Modification
Phospho
货号: YP1843
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
详细信息
推荐稀释比
WB 1:500-2000; IHC 1:50-200
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of Caveolin 2 (Phospho Ser23) Rabbit pAb at Human, Mouse,Rat
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
26kD
修饰
Phospho
克隆性
Polyclonal
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
预览→
Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
预览→
Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
预览→
Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029
预览→
抗原&靶点信息
免疫原:
Synthesized peptide derived from human Caveolin 2 (Phospho Ser23)
展开内容
特异性:
This antibody detects endogenous levels of Caveolin 2 (Phospho Ser23) Rabbit pAb at Human, Mouse,Rat
展开内容
基因名称:
CAV2
展开内容
蛋白名称:
Caveolin-2
展开内容
别名:
CAV2 ;
Caveolin-2
Caveolin-2
展开内容
背景:
caveolin 2(CAV2) Homo sapiens The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462). [provided by RefSeq, May 2011],
展开内容
功能:
Function:May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.,Function:May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-2 may function as an accessory protein in conjunction with caveolin-1.,online information:Caveolin entry,similarity:Belongs to the caveolin family.,subcellular location:Potential hairpin-like structure in the membrane. Membrane protein of caveolae.,subunit:Homodimer. Caveolin-1 and -2 colocalize and form a stable hetero-oligomeric complex.,tissue specificity:Expressed in endothelial cells, smooth muscle cells, skeletal myoblasts and fibroblasts.,
展开内容
细胞定位:
Nucleus. Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Potential hairpin-like structure in the membrane. Membrane protein of caveolae. Tyr-19-phosphorylated form is enriched at sites of cell-cell contact and is translocated to the nucleus in complex with MAPK1 in response to insulin (By similarity). Tyr-27-phosphorylated form is located both in the cytoplasm and plasma membrane. CAV1-mediated Ser-23-phosphorylated form locates to the plasma membrane. Ser-36-phosphorylated form resides in intracellular compartments. .
展开内容
研究领域:
>>Endocytosis ;
>>Focal adhesion ;
>>Prion disease ;
>>Bacterial invasion of epithelial cells ;
>>Proteoglycans in cancer ;
>>Fluid shear stress and atherosclerosis
>>Focal adhesion ;
>>Prion disease ;
>>Bacterial invasion of epithelial cells ;
>>Proteoglycans in cancer ;
>>Fluid shear stress and atherosclerosis
展开内容
信号通路
文献引用（{{totalcount}}）
货号: YP1843
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
Recently Viewed Products
Clear all
×
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
主要信息
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
产品 {{index}}/{{pcount}}
上一个产品
下一个产品
{{pvTitle}}
滚轮缩放图片
{{pvDescr}}