CD31 (Phospho Tyr690) Rabbit pAb
-YP1836
主要信息
Target
CD31 Phospho Tyr690
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IHC, WB
MW
85-130kD (Observed)
Conjugate/Modification
Phospho
货号: YP1836
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; IHC 1:50-200
组成
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of CD31 (Phospho Tyr690) Rabbit pAb at Human, Mouse,Rat
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
85-130kD
修饰
Phospho
克隆性
Polyclonal
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human CD31 (Phospho Tyr690)
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特异性:
This antibody detects endogenous levels of CD31 (Phospho Tyr690) Rabbit pAb at Human, Mouse,Rat
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基因名称:
PECAM1
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蛋白名称:
Platelet endothelial cell adhesion molecule (PECAM-1) (EndoCAM) (GPIIA') (PECA1) (CD antigen CD31)
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别名:
Platelet endothelial cell adhesion molecule ;
PECAM-1 ;
EndoCAM ;
GPIIA' ;
PECA1 ;
CD antigen CD31 ;
PECAM-1 ;
EndoCAM ;
GPIIA' ;
PECA1 ;
CD antigen CD31 ;
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背景:
platelet and endothelial cell adhesion molecule 1(PECAM1) Homo sapiens The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010],
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功能:
Function:This protein is a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions.,online information:CD31 entry,online information:PECAM-1,online information:The Singapore human mutation and polymorphism database,PTM:Phosphorylated on Ser and Tyr residues after cellular activation.,similarity:Contains 6 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Long isoform predominates all tissues examined, isoform Delta12 was detected only in trachea and isoform Delta14-15 only in lung, isoform Delta14 was detected in all tissues examined with the strongest expression in heart.,
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细胞定位:
Cell membrane ; Single-pass type I membrane protein . Cell surface expression on neutrophils is down-regulated upon fMLP or CXCL8/IL8-mediated stimulation. .; [Isoform Long]: Cell membrane ; Single-pass type I membrane protein . Membrane raft . Cell junction . Localizes to the lateral border recycling compartment (LBRC) and recycles from the LBRC to the junction in resting endothelial cells. .; [Isoform Delta15]: Cell junction . Localizes to the lateral border recycling compartment (LBRC) and recycles from the LBRC to the junction in resting endothelial cells.
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研究领域:
>>Cell adhesion molecules ;
>>Leukocyte transendothelial migration ;
>>Malaria ;
>>Fluid shear stress and atherosclerosis
>>Leukocyte transendothelial migration ;
>>Malaria ;
>>Fluid shear stress and atherosclerosis
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信号通路
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货号: YP1836
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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