eIF2β (Phospho Ser67) Rabbit pAb
-YP1615
主要信息
Target
eIF2β Phospho Ser67
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW
69kD (Observed)
Conjugate/Modification
Phospho
货号: YP1615
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
WB 1:1000-2000; ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of Human eIF2B (Phospho Ser67).The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):DAsDD
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
实测条带
69kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human eIF2B (Phospho Ser67)
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特异性:
This antibody detects endogenous levels of Human eIF2B (Phospho Ser67).The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):DAsDD
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基因名称:
EIF2S2 EIF2B
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蛋白名称:
eIF2B (Phospho Ser67)
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别名:
EIF2S2 ;
EIF2B ;
Eukaryotic translation initiation factor 2 subunit 2 ;
Eukaryotic translation initiation factor 2 subunit beta ;
eIF-2-beta
EIF2B ;
Eukaryotic translation initiation factor 2 subunit 2 ;
Eukaryotic translation initiation factor 2 subunit beta ;
eIF-2-beta
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背景:
eukaryotic translation initiation factor 2 subunit beta (EIF2S2) Homo sapiens Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits , alpha , beta , and gamma , with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP , which recycles the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq , Oct 2015] ,
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功能:
Function:eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit , followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation , the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B. ,similarity:Belongs to the eIF-2-beta/eIF-5 family. ,subunit:Heterotrimer composed of an alpha , a beta and a gamma chain. Component of an EIF2 complex at least composed of CUGBP1 , CALR , CALR3 , EIF2S1 , EIF2S2 , HSP90B1 and HSPA5. ,
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货号: YP1615
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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