CRMP1 (Phospho Tyr504) Rabbit pAb
-YP1756
主要信息
Target
CRMP1 Phospho Tyr504
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
63kD (Calculated)
Conjugate/Modification
Phospho
货号: YP1756
规格
价格
货期
数量
200μL
￥4,680.00
两周
0
100μL
￥2,800.00
两周
0
50μL
￥1,500.00
两周
0
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详细信息
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of CRMP-1 (Phospho-Tyr504) at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):PVyEV
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
63kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
抗原&靶点信息
免疫原:
Synthesized peptide derived from human CRMP-1 (Phospho-Tyr504)
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特异性:
This antibody detects endogenous levels of CRMP-1 (Phospho-Tyr504) at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):PVyEV
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基因名称:
CRMP1 DPYSL1 ULIP3
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蛋白名称:
Dihydropyrimidinase-related protein 1
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别名:
DPYL1 ;
Dihydropyrimidinase-related protein 1 ;
DRP-1 ;
Collapsin response mediator protein 1 ;
CRMP-1 ;
Unc-33-like phosphoprotein 3 ;
ULIP-3 ;
Dihydropyrimidinase-related protein 1 ;
DRP-1 ;
Collapsin response mediator protein 1 ;
CRMP-1 ;
Unc-33-like phosphoprotein 3 ;
ULIP-3 ;
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背景:
This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008],
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功能:
Function:Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.,similarity:Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.,subcellular location:Associated with centrosomes and the mitotic spindle during metaphase.,subunit:Homotetramer, and heterotetramer with DPYSL2, DPYSL3, DPYSL4 or DPYSL5. Interacts with PLXNA1.,tissue specificity:Brain.,
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细胞定位:
Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Cell projection, growth cone . Cytoplasm, cytoskeleton . Perikaryon . Associated with centrosomes and the mitotic spindle during metaphase (PubMed:11562390). Colocalizes with FLNA and tubulin in the central region of DRG neuron growth cone (By similarity). Following SEMA3A stimulation of DRG neurons, colocalizes with F-actin (By similarity). .
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组织表达:
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文献引用（{{totalcount}}）
货号: YP1756
规格
价格
货期
数量
200μL
￥4,680.00
两周
0
100μL
￥2,800.00
两周
0
50μL
￥1,500.00
两周
0
加入购物车
已收藏
收藏
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