Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

CNTF

Ciliary neurotrophic factor

CNTF ;
Ciliary neurotrophic factor ;
CNTF

disease:Overexpressed in most acute myelogenous leukemia (AML) cases (27 over 29).,function:CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.,function:May be involved in transcriptional regulation. May play an important role in cell proliferation and/or anti-apoptosis.,online information:Ciliary neurotrophic factor entry,similarity:Belongs to the CNTF family.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 5 C2H2-type zinc fingers.,subunit:Homodimer.,tissue specificity:Expressed ubiquitously, particularly at high level in testis. Isoform 2 is testis specific.,tissue specificity:Nervous system.,

regulation of cell growth, cell activation, regulation of protein amino acid phosphorylation, positive regulation of protein amino acid phosphorylation, transcription, protein complex assembly, cellular ion homeostasis, muscle organ development, positive regulation of cell proliferation, regulation of cell size, positive regulation of signal transduction,glial cell differentiation, positive regulation of phosphorus metabolic process, positive regulation of macromolecule metabolic process, regulation of protein kinase cascade, positive regulation of cell communication, positive regulation of cell development, positive regulation of protein kinase cascade, regulation of cell morphogenesis involved in differentiation, regulation of cell death, regulation of neuron projection development, positive regulation of neuron projection development, astrocyte development, regulation of phosphoinositide 3-kinase cascade, positive regulation of phosphoinositide 3-kinase cascade, regulation of phosphate metabolic process, cytokine-mediated signaling pathway, cellular homeostasis, glial cell development, regulation of cell morphogenesis, neuron differentiation,positive regulation of cell growth, regulation of cell projection organization, positive regulation of cell projection organization, regulation of protein modification process, positive regulation of protein modification process, regulation of response to external stimulus, positive regulation of response to external stimulus, regulation of cellular protein metabolic process, positive regulation of cellular protein metabolic process, regulation of cellular component size,growth, regulation of growth, gliogenesis, regulation of cell proliferation, regulation of phosphorylation, positive regulation of phosphorylation, regulation of membrane potential, regulation of tyrosine phosphorylation of STAT protein, regulation of tyrosine phosphorylation of Stat3 protein, positive regulation of tyrosine phosphorylation of Stat3 protein, positive regulation of tyrosine phosphorylation of STAT protein, homeostatic process, regulation of apoptosis, negative regulation of apoptosis, regulation of programmed cell death, negative regulation of programmed cell death, regulation of MAPKKK cascade, positive regulation of MAPKKK cascade, regulation of neuron apoptosis,negative regulation of neuron apoptosis, neuroprotection, macromolecular complex subunit organization, regulation of transcription, negative regulation of cell differentiation, positive regulation of cell differentiation, regulation of neuron differentiation, negative regulation of neuron differentiation, positive regulation of cell size, positive regulation of growth, positive regulation of phosphate metabolic process, regulation of JAK-STAT cascade, positive regulation of JAK-STAT cascade, regulation of photoreceptor cell differentiation, negative regulation of photoreceptor cell differentiation, regulation of retinal cell programmed cell death, regulation of hormone secretion, positive regulation of hormone secretion, astrocyte activation, positive regulation of response to stimulus, muscle organ morphogenesis,neuron development, regulation of axon regeneration, positive regulation of axon regeneration, astrocyte differentiation, chemical homeostasis, regulation of peptidyl-tyrosine phosphorylation, positive regulation of peptidyl-tyrosine phosphorylation, regulation of neurogenesis, positive regulation of neurogenesis, regulation of axonogenesis, positive regulation of axonogenesis, ion homeostasis, regulation of secretion, positive regulation of secretion, positive regulation of transport, positive regulation of developmental process, positive regulation of cellular component organization, regulation of phosphorus metabolic process, negative regulation of multicellular organismal process, positive regulation of protein metabolic process, protein oligomerization, protein heterooligomerization,regulation of nervous system development, cellular chemical homeostasis, regulation of resting membrane potential,membrane hyperpolarization, regulation of cell development, regulation of cellular localization, negative regulation of cell death, macromolecular complex assembly, ciliary neurotrophic factor-mediated signaling pathway, protein complex biogenesis, regulation of neuron projection regeneration, positive regulation of neuron projection regeneration,regulation of cellular response to stress,

Cytoplasm.

Nervous system.