eIF6 (Phospho Ser235) Rabbit pAb
-YP1728
主要信息
Target
EIF6 Phospho Ser235
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
27kD (Calculated)
Conjugate/Modification
Phospho
货号: YP1728
规格
价格
货期
数量
200μL
￥4,680.00
两周
0
100μL
￥2,800.00
两周
0
50μL
￥1,500.00
两周
0
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详细信息
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of EIF6 (Phospho-Ser235) at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):ATsMR
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
27kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human EIF6 (Phospho-Ser235)
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特异性:
This antibody detects endogenous levels of EIF6 (Phospho-Ser235) at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):ATsMR
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基因名称:
EIF6 EIF3A ITGB4BP OK/SW-cl.27
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蛋白名称:
EIF6 (Phospho-Ser235)
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别名:
IF6 ;
Eukaryotic translation initiation factor 6 ;
eIF-6 ;
B ;
2 ;
GCN homolog ;
B4 integrin interactor ;
CAB ;
p27 ;
BBP ;
Eukaryotic translation initiation factor 6 ;
eIF-6 ;
B ;
2 ;
GCN homolog ;
B4 integrin interactor ;
CAB ;
p27 ;
BBP ;
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背景:
Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2012],
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功能:
Function:Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex.,similarity:Belongs to the eIF-6 family.,subunit:Monomer.,
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细胞定位:
Cytoplasm. Nucleus, nucleolus. Shuttles between cytoplasm and nucleus/nucleolus.
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研究领域:
>>Ribosome biogenesis in eukaryotes
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文献引用（{{totalcount}}）
货号: YP1728
规格
价格
货期
数量
200μL
￥4,680.00
两周
0
100μL
￥2,800.00
两周
0
50μL
￥1,500.00
两周
0
加入购物车
已收藏
收藏
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