TAZ (Phospho Ser89) Rabbit pAb
-YP1526
主要信息
Target
TAZ Phospho Ser89
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
44kD (Observed)
Conjugate/Modification
Phospho
货号: YP1526
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of Human Mouse Rat TAZ (phospho-Ser89)
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
实测条带
44kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized phosho peptide around human TAZ (Ser89)
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特异性:
This antibody detects endogenous levels of Human Mouse Rat TAZ (phospho-Ser89)
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基因名称:
WWTR1 TAZ
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蛋白名称:
WW domain-containing transcription regulator protein 1
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别名:
WW domain-containing transcription regulator protein 1 ;
Transcriptional coactivator with PDZ-binding motif ;
Transcriptional coactivator with PDZ-binding motif ;
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功能:
Domain:Binds to transcription factors via its WW domain. ,Domain:The PDZ-binding motif is essential for stimulated gene transcription. It localizes the protein into both punctate nuclear foci and plasma membrane-associated complexes. ,Function:Functions as a transcriptional coactivator. ,PTM:Phosphorylated. Phosphorylation results in the inhibition of transcriptional coactivation through YWHAZ-mediated nuclear export. ,similarity:Contains 1 WW domain. ,subcellular location:Concentrates along specific portions of the plasma membrane , and accumulates in punctate nuclear bodies. When phosphorylated , is retained in cytoplasm by YWHAZ. ,subunit:Binds to SLC9A3R2 via the PDZ motif at the plasma membrane. Binds to YWHAZ in vivo and in vitro through the phosphoserine-binding motif RSHSSP. ,tissue specificity:Highly expressed in kidney , heart , placenta and lung. ,
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细胞定位:
Nucleus . Cytoplasm . Cell membrane . Concentrates along specific portions of the plasma membrane , and accumulates in punctate nuclear bodies (By similarity) . When phosphorylated , is retained in the cytoplasm by YWHAZ (By similarity) . Can be retained in the nucleus by MED15 (PubMed:18568018) . Localized in the cytoplasm in areas of epithelial cell high density (PubMed:21145499) . At blastocyst stage expressed in the nucleus in trophectodermal cells , however expressed in the cytoplasm in the inner cell mass (By similarity) . .
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研究领域:
>>Hippo signaling pathway ;
>>Hippo signaling pathway - multiple species
>>Hippo signaling pathway - multiple species
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信号通路
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货号: YP1526
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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