PEPC (Phospho Ser15) Rabbit pAb
-YP1636
主要信息
Target
phosphoenolpyruvate carboxylase Phospho Ser15
Host Species
Rabbit
Reactivity
A.comosus, A.thaliana, H.vulgare, J.curcas, M.crystallinum, N.tabacum, Z.mays, T.weissfloggi
Applications
WB, ELISA, IHC
MW
105-110kD (Observed)
Conjugate/Modification
Phospho
货号: YP1636
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
组成
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
特异性
The antibody detects endogenous PEPC (Phospho Ser15) protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
实测条带
105-110kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthetic Peptide of PEPC (Phospho Ser15)
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特异性:
The antibody detects endogenous PEPC (Phospho Ser15) protein.
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基因名称:
PGC
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蛋白名称:
Phosphoenolpyruvate carboxylase
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别名:
PGC ;
Gastricsin ;
Pepsinogen C
Gastricsin ;
Pepsinogen C
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背景:
This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009],
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功能:
Catalytic activity:More restricted specificity than pepsin A, but shows preferential cleavage at Tyr-|-Xaa bonds. High activity on hemoglobin.,Function:Hydrolyzes a variety of proteins.,similarity:Belongs to the peptidase A1 family.,
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细胞定位:
Secreted.
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组织表达:
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货号: YP1636
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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