SCRIB (Phospho Ser1220) Rabbit pAb
-YP1479
主要信息
Target
SCRIB Phospho Ser1220
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, ELISA, IHC
MW
179kD (Observed)
Conjugate/Modification
Phospho
货号: YP1479
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of Human Mouse Scribble (phospho-Ser1220)
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
179kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized phosho peptide around human Scribble (Ser1220)
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特异性:
This antibody detects endogenous levels of Human Mouse Scribble (phospho-Ser1220)
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基因名称:
SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL
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蛋白名称:
Protein scribble homolog
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别名:
Protein scribble homolog ;
Scribble ;
hScrib ;
Protein LAP4 ;
Scribble ;
hScrib ;
Protein LAP4 ;
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背景:
This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011],
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功能:
similarity:Contains 4 PDZ (DHR) domains.,
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细胞定位:
Cell membrane ; Peripheral membrane protein. Cell junction . Cell junction, adherens junction. Cell projection, lamellipodium. Cytoplasm. Cell junction, synapse, postsynapse . Cell junction, synapse, presynapse . Targeting to cell-cell junctions which is CDH1-dependent is required for the pro-apoptotic activity. In a subset of CD4+ T-cells, colocalizes with CRTAM at the immunological synapse during the late phase of T-cell activation (By similarity). .
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研究领域:
>>Hippo signaling pathway ;
>>Tight junction ;
>>Human papillomavirus infection ;
>>Viral carcinogenesis
>>Tight junction ;
>>Human papillomavirus infection ;
>>Viral carcinogenesis
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信号通路
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货号: YP1479
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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