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RPA32/RPA2 (Phospho Ser8) Rabbit pAb

-YP1470

5 2
主要信息
Target

RPA2 Phospho Ser8

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB

MW

32kD (Observed)

Conjugate/Modification

Phospho

货号: YP1470
规格
价格
货期
数量
200μL
¥4,680.00
现货

0

100μL
¥2,800.00
现货

0

50μL
¥1,500.00
现货

0

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详细信息
推荐稀释比
WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of Human RPA32 or RPA2 (phospho-Ser8)
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
32kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
相关产品
Primary Antibodies
RPA32/RPA2 Rabbit pAb
YT4170

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Primary Antibodies
RPA32/RPA2 (Phospho Thr21) Rabbit pAb
YP0743

预览→

Primary Antibodies
RPA32/RPA2 (Phospho Ser33) Rabbit pAb
YP0476

预览→

ELISA Kits
Total RFA2 Cell-Based Colorimetric ELISA Kit
KA4267C

预览→

ELISA Kits
RFA2 (Phospho Ser33) Cell-Based Colorimetric ELISA Kit
KA1758C

预览→

ELISA Kits
RFA2 (Phospho Thr21) Cell-Based Colorimetric ELISA Kit
KA1472C

预览→

抗原&靶点信息
免疫原:
Synthesized phosho peptide around human RPA32 and RPA2 (Ser8)
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特异性:
This antibody detects endogenous levels of Human RPA32 or RPA2 (phospho-Ser8)
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基因名称:
RPA2 REPA2 RPA32 RPA34
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蛋白名称:
RPA32/RPA2 (Ser8)
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别名:
Replication protein A 32 kDa subunit ;
RP-A p32 ;
Replication factor A protein 2 ;
RF-A protein 2 ;
Replication protein A 34 kDa subunit ;
RP-A p34 ;
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数据库链接:
Organism 基因 ID SwissProt
Human 6118; P15927;
Mouse Q62193;
Rat 59102; Q63528;
功能:
Function:Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.,PTM:Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC/DNA-PK in the presence of Ku and DNA, and by CDC2.,subcellular location:Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Binds to SERTAD3/RBT1. Interacts with TIPIN.,
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细胞定位:
Nucleus . Nucleus, PML body . Redistributes to discrete nuclear foci upon DNA damage in an ATR-dependent manner. .
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组织表达:
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研究领域:
>>DNA replication ;
>>Nucleotide excision repair ;
>>Mismatch repair ;
>>Homologous recombination ;
>>Fanconi anemia pathway
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货号: YP1470
规格
价格
货期
数量
200μL
¥4,680.00
现货

0

100μL
¥2,800.00
现货

0

50μL
¥1,500.00
现货

0

加入购物车

已收藏

收藏

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