RIP2 (Phospho Ser176) Rabbit pAb
-YP1223
主要信息
Target
RIP2 Phospho Ser176
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA, IHC
MW
61kD (Observed)
Conjugate/Modification
Phospho
货号: YP1223
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This detects endogenous levels of RIPK2 (Phospho-Ser176).The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):SLsQS
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
实测条带
61kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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ELISA Kits
Total RIPK2 Cell-Based Colorimetric ELISA Kit
KA4270C
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ELISA Kits
RIPK2 (Phospho Ser176) Cell-Based Colorimetric ELISA Kit
KA1721C
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抗原&靶点信息
免疫原:
Synthesized phospho derived from human RIPK2 (Phospho-Ser176)
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特异性:
This detects endogenous levels of RIPK2 (Phospho-Ser176).The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):SLsQS
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基因名称:
RIPK2 CARDIAK RICK RIP2 UNQ277/PRO314/PRO34092
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蛋白名称:
Receptor-interacting serine/threonine-protein kinase 2 (CARD-containing interleukin-1 beta-converting enzyme-associated kinase) (CARD-containing IL-1 beta ICE-kinase) (RIP-like-interacting CLARP kinase) (Receptor-interacting protein 2) (RIP-2) (Tyrosine-protein kinase RIPK2) (EC 2.7.10.2)
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别名:
Receptor-interacting serine/threonine-protein kinase 2 ;
CARD-containing interleukin-1 beta-converting enzyme-associated kinase ;
CARD-containing IL-1 beta ICE-kinase ;
RIP-like-interacting CLARP kinase ;
Receptor-interacting protein 2 ;
RIP-2 ;
Tyrosine-protein kinase RIPK2 ;
CARD-containing interleukin-1 beta-converting enzyme-associated kinase ;
CARD-containing IL-1 beta ICE-kinase ;
RIP-like-interacting CLARP kinase ;
Receptor-interacting protein 2 ;
RIP-2 ;
Tyrosine-protein kinase RIPK2 ;
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背景:
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD) , and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. [provided by RefSeq , Jul 2008] ,
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功能:
Catalytic activity:ATP + a protein = ADP + a phosphoprotein. ,Function:Activates pro-caspase-1 and pro-caspase-8. Potentiates CASP8-mediated apoptosis. Activates NF-kappa-B. ,PTM:Autophosphorylated. Phosphorylated upon DNA damage , probably by ATM or ATR. ,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. ,similarity:Contains 1 CARD domain. ,similarity:Contains 1 protein kinase domain. ,subunit:Binds to CFLAR/CLARP and CASP1 via their CARD domains. Binds to BIRC3/c-IAP1 and BIRC2/c-IAP2 , TRAF1 , TRAF2 , TRAF5 and TRAF6. May be a component of both the TNFRSF1A and TNRFSF5/CD40 receptor complex. ,tissue specificity:Detected in heart , brain , placenta , lung , peripheral blood leukocytes , spleen , kidney , testis , prostate , pancreas and lymph node. ,
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细胞定位:
Cytoplasm .
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研究领域:
>>NOD-like receptor signaling pathway ;
>>Neurotrophin signaling pathway ;
>>Shigellosis ;
>>Salmonella infection ;
>>Tuberculosis
>>Neurotrophin signaling pathway ;
>>Shigellosis ;
>>Salmonella infection ;
>>Tuberculosis
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信号通路
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货号: YP1223
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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