GIT2 (Phospho Tyr392) Rabbit pAb
-YP1347
主要信息
Target
GIT2 Phospho Tyr392
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
84kD (Observed)
Conjugate/Modification
Phospho
货号: YP1347
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of Human GIT2 (phospho-Tyr392)
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
84kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized phosho peptide around human GIT2 (Tyr392)
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特异性:
This antibody detects endogenous levels of Human GIT2 (phospho-Tyr392)
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基因名称:
GIT2 KIAA0148
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蛋白名称:
GIT2 (Tyr392)
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别名:
ARF GTPase-activating protein GIT2 ;
ARF GAP GIT2 ;
Cool-interacting tyrosine-phosphorylated protein 2 ;
CAT-2 ;
CAT2 ;
G protein-coupled receptor kinase-interactor 2 ;
GRK-interacting protein 2 ;
ARF GAP GIT2 ;
Cool-interacting tyrosine-phosphorylated protein 2 ;
CAT-2 ;
CAT2 ;
G protein-coupled receptor kinase-interactor 2 ;
GRK-interacting protein 2 ;
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背景:
This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G
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功能:
Alternative products:Additional isoforms seem to exist,Function:GTPase-activating protein for the ADP ribosylation factor family.,similarity:Contains 1 Arf-GAP domain.,similarity:Contains 3 ANK repeats.,subunit:Interacts with TGFB1I1 (By similarity). Interacts with G protein-coupled receptor kinases. Associates with paxillin. Also interacts with PIX exchange factors.,
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细胞定位:
nucleoplasm,focal adhesion,
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研究领域:
>>Endocytosis ;
>>Yersinia infection
>>Yersinia infection
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货号: YP1347
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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