Function:Potent transcriptional repressor that binds to the H1 element of the Ets2 promoter. May regulate other genes involved in cellular proliferation. Required for extraembryonic ectoderm differentiation , ectoplacental cone cavity closure , and chorioallantoic attachment (By similarity) . May be important for regulating trophoblast stem cell differentiation. ,PTM:Phosphorylated by multiple kinases including probably ERK2. Phosphorylation regulates the activity of ERF. ,sequence Caution:The sequence differs from that shown because it seems to be derived from a pre-mRNA. ,similarity:Belongs to the ETS family. ,similarity:Contains 1 ETS DNA-binding domain. ,tissue specificity:Highest levels in testis , ovary , pancreas , and heart. ,
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