JDP2 (Phospho Thr148) Rabbit pAb
-YP1099
主要信息
Target
JDP2 Phospho Thr148
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IHC, IF, ELISA
MW
19kD (Calculated)
Conjugate/Modification
Phospho
货号: YP1099
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Phospho-JDP2 (T148) Polyclonal Antibody detects endogenous levels of JDP2 protein only when phosphorylated at T148.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):VKtPE
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
19kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human JDP-2 around the phosphorylation site of Thr148. AA range:114-163
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特异性:
Phospho-JDP2 (T148) Polyclonal Antibody detects endogenous levels of JDP2 protein only when phosphorylated at T148.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):VKtPE
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基因名称:
JDP2
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蛋白名称:
Jun dimerization protein 2
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别名:
JDP2 ;
Jun dimerization protein 2
Jun dimerization protein 2
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背景:
function:Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis , cell differentiation , tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin. ,PTM:Phosphorylation of Thr-148 by MAPK8 in response to different stress conditions such as , UV irradiation , oxidatives stress and anisomycin treatments. ,similarity:Belongs to the bZIP family. ATF subfamily. ,similarity:Contains 1 bZIP domain. ,subunit:Forms homodimer or heterodimer with JUN , JUNB , JUND , CEBPG and ATF2 thereby inhibiting transactivation by JUN , ATF2 and CEBPG (By similarity) . Binds multiple DNA elements such as cAMP-response element (CRE) and TPA response element (TRE) either as homodimer or heterodimer. ,
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功能:
Function:Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis , cell differentiation , tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin. ,PTM:Phosphorylation of Thr-148 by MAPK8 in response to different stress conditions such as , UV irradiation , oxidatives stress and anisomycin treatments. ,similarity:Belongs to the bZIP family. ATF subfamily. ,similarity:Contains 1 bZIP domain. ,subunit:Forms homodimer or heterodimer with JUN , JUNB , JUND , CEBPG and ATF2 thereby inhibiting transactivation by JUN , ATF2 and CEBPG (By similarity) . Binds multiple DNA elements such as cAMP-response element (CRE) and TPA response element (TRE) either as homodimer or heterodimer. ,
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细胞定位:
Nucleus .
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组织表达:
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货号: YP1099
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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