NFAT5 (Phospho Ser1197) Rabbit pAb
-YP1195
主要信息
Target
NFAT5 Phospho Ser1197
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IHC, IF, ELISA
MW
166kD (Calculated)
Conjugate/Modification
Phospho
货号: YP1195
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; IHC 1:50-300; IF 1:200-1:1000; ELISA 5000-1:20000;
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Phospho-NFAT5 (S1197) Polyclonal Antibody detects endogenous levels of NFAT5 protein only when phosphorylated at S1197.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):MLsQE
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
166kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human NFAT5 around the phosphorylation site of Ser1197. AA range:1171-1220
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特异性:
Phospho-NFAT5 (S1197) Polyclonal Antibody detects endogenous levels of NFAT5 protein only when phosphorylated at S1197.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):MLsQE
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基因名称:
NFAT5
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蛋白名称:
Nuclear factor of activated T-cells 5
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别名:
NFAT5 ;
KIAA0827 ;
TONEBP ;
Nuclear factor of activated T-cells 5 ;
NF-AT5 ;
T-cell transcription factor NFAT5 ;
Tonicity-responsive enhancer-binding protein ;
TonE-binding protein ;
TonEBP
KIAA0827 ;
TONEBP ;
Nuclear factor of activated T-cells 5 ;
NF-AT5 ;
T-cell transcription factor NFAT5 ;
Tonicity-responsive enhancer-binding protein ;
TonE-binding protein ;
TonEBP
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背景:
The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
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功能:
Alternative products:Experimental confirmation may be lacking for some isoforms,Function:Plays a role in the inducible expression of genes. Regulates hypertonicity-induced cellular accumulation of osmolytes.,similarity:Contains 1 RHD (Rel-like) domain.,subunit:Does not bind with Fos and Jun transcription factors. But might be capable of forming stable dimers with DNA elements.,tissue specificity:Highest levels in skeletal muscle, brain, heart and peripheral blood leukocytes. Also expressed in placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine and colon.,
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细胞定位:
Nucleus . Cytoplasm . Nuclear distribution increases under hypertonic conditions. .
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货号: YP1195
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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