Adducin α (Phospho Thr445) Rabbit pAb
-YP0955
主要信息
Target
ADD1 Phospho Thr445
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IHC, IF, ELISA
MW
81kD (Calculated)
Conjugate/Modification
Phospho
货号: YP0955
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Phospho-Adducin α (T445) Polyclonal Antibody detects endogenous levels of Adducin α protein only when phosphorylated at T445.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):EKtRW
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
81kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human ADD1 around the phosphorylation site of Thr445. AA range:411-460
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特异性:
Phospho-Adducin α (T445) Polyclonal Antibody detects endogenous levels of Adducin α protein only when phosphorylated at T445.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):EKtRW
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基因名称:
ADD1
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蛋白名称:
Alpha-adducin
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别名:
ADD1 ;
ADDA ;
Alpha-adducin ;
Erythrocyte adducin subunit alpha
ADDA ;
Alpha-adducin ;
Erythrocyte adducin subunit alpha
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背景:
adducin 1 (ADD1) Homo sapiens Adducins are a family of cytoskeleton proteins encoded by three genes (alpha , beta , gamma) . Adducin is a heterodimeric protein that consists of related subunits , which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive , hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast , beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca (2+) /calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however , not all variants have been fully described. [provided by RefSeq , Jul 2008] ,
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功能:
Alternative products:Additional isoforms seem to exist ,Domain:Each subunit is comprised of three regions: a NH2-terminal protease-resistant globular head region , a short connecting subdomain , and a protease-sensitive tail region. ,Function:Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin. ,PTM:The N-terminus is blocked. ,similarity:Belongs to the aldolase class II family. Adducin subfamily. ,subunit:Heterodimer of an alpha and a beta subunit or an alpha and a gamma subunit. Binds ROCK1. ,tissue specificity:Expressed in all tissues. Found in much higher levels in reticulocytes than the beta subunit. ,
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细胞定位:
Cytoplasm , cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
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文献引用（{{totalcount}}）
货号: YP0955
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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