APLF (Phospho Ser116) Rabbit pAb
-YP1078
主要信息
Target
APLF Phospho Ser116
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
IHC, IF, ELISA
MW
57kD (Calculated)
Conjugate/Modification
Phospho
货号: YP1078
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
详细信息
推荐稀释比
IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Phospho-APLF (S116) Polyclonal Antibody detects endogenous levels of APLF protein only when phosphorylated at S116.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RNsQV
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
57kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
预览→
Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
预览→
Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
预览→
Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029
预览→
抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human APLF around the phosphorylation site of Ser116. AA range:82-131
展开内容
特异性:
Phospho-APLF (S116) Polyclonal Antibody detects endogenous levels of APLF protein only when phosphorylated at S116.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RNsQV
展开内容
基因名称:
APLF
展开内容
蛋白名称:
Aprataxin and PNK-like factor
展开内容
别名:
APLF ;
C2orf13 ;
PALF ;
XIP1 ;
Aprataxin and PNK-like factor ;
Apurinic-apyrimidinic endonuclease APLF ;
PNK and APTX-like FHA domain-containing protein ;
XRCC1-interacting protein 1
C2orf13 ;
PALF ;
XIP1 ;
Aprataxin and PNK-like factor ;
Apurinic-apyrimidinic endonuclease APLF ;
PNK and APTX-like FHA domain-containing protein ;
XRCC1-interacting protein 1
展开内容
背景:
C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks (Iles et al., 2007 [PubMed 17353262]).[supplied by OMIM, Mar 2008],
展开内容
功能:
Domain:The FHA-like domain mediates interaction with XRCC1 and XRCC4.,Function:Involved in single-strand and double-strand DNA break repair.,PTM:Phosphorylated in an ATM-dependent manner upon double-strand DNA break.,similarity:Contains 1 FHA-like domain.,similarity:Contains 2 C2H2-type zinc fingers.,subcellular location:Colocalizes with XRCC1 at sites of DNA damage.,subunit:Interacts with XRCC1. May also interact with XRCC4 and XRCC5.,
展开内容
细胞定位:
Nucleus . Chromosome . Cytoplasm, cytosol . Localizes to DNA damage sites (PubMed:18474613, PubMed:18172500, PubMed:21211721, PubMed:23689425). Accumulates at single-strand breaks and double-strand breaks via the PBZ-type zinc fingers (PubMed:18172500). .
展开内容
组织表达:
展开内容
文献引用（{{totalcount}}）
货号: YP1078
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
Recently Viewed Products
Clear all
×
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
主要信息
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
产品 {{index}}/{{pcount}}
上一个产品
下一个产品
{{pvTitle}}
滚轮缩放图片
{{pvDescr}}