Casein Kinase Iγ1/2/3 (Phospho Tyr263) Rabbit pAb
-YP1040
主要信息
Target
Casein Kinase Iγ1/2/3 Phospho Tyr263
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IHC, IF, ELISA
MW
50kD (Calculated)
Conjugate/Modification
Phospho
货号: YP1040
规格
价格
货期
数量
200μL
￥4,680.00
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0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Phospho-Casein Kinase Iγ1/2/3 (Y263) Polyclonal Antibody detects endogenous levels of Casein Kinase Iγ1/2/3 protein only when phosphorylated at Y263.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):ERyQK
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
50kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human CK-1 gamma1/2/3 around the phosphorylation site of Tyr263. AA range:229-278
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特异性:
Phospho-Casein Kinase Iγ1/2/3 (Y263) Polyclonal Antibody detects endogenous levels of Casein Kinase Iγ1/2/3 protein only when phosphorylated at Y263.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):ERyQK
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基因名称:
CSNK1G1/CSNK1G2/CSNK1G3
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蛋白名称:
Casein kinase I isoform gamma-1/2/3
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别名:
CSNK1G1 ;
Casein kinase I isoform gamma-1 ;
CKI-gamma 1 ;
CSNK1G2 ;
CK1G2 ;
Casein kinase I isoform gamma-2 ;
CKI-gamma 2 ;
CSNK1G3 ;
Casein kinase I isoform gamma-3 ;
CKI-gamma 3
Casein kinase I isoform gamma-1 ;
CKI-gamma 1 ;
CSNK1G2 ;
CK1G2 ;
Casein kinase I isoform gamma-2 ;
CKI-gamma 2 ;
CSNK1G3 ;
Casein kinase I isoform gamma-3 ;
CKI-gamma 3
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数据库链接:
背景:
This gene encodes a member of the casein kinase I gene family. This family is comprised of serine/threonine kinases that phosphorylate acidic proteins such as caseins. The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin. A mutation in this gene may be associated with non-syndromic early-onset epilepsy (NSEOE). [provided by RefSeq, Jul 2016],
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功能:
Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,Function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer.,
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细胞定位:
Cytoplasm.
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组织表达:
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研究领域:
>>Hedgehog signaling pathway
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货号: YP1040
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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