BAM32 (Phospho Tyr139) Rabbit pAb
-YP0549
主要信息
Target
DAPP1 Phospho Tyr139
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IHC, IF, ELISA
MW
32kD (Observed)
Conjugate/Modification
Phospho
货号: YP0549
规格
价格
货期
数量
200μL
￥4,680.00
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0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
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0
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详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Phospho-BAM32 (Y139) Polyclonal Antibody detects endogenous levels of BAM32 protein only when phosphorylated at Y139.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):SIyES
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
实测条带
32kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human DAPP1 around the phosphorylation site of Tyr139. AA range:105-154
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特异性:
Phospho-BAM32 (Y139) Polyclonal Antibody detects endogenous levels of BAM32 protein only when phosphorylated at Y139.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):SIyES
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基因名称:
DAPP1
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蛋白名称:
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
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别名:
DAPP1 ;
BAM32 ;
HSPC066 ;
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide ;
hDAPP1 ;
B lymphocyte adapter protein Bam32 ;
B-cell adapter molecule of 32 kDa
BAM32 ;
HSPC066 ;
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide ;
hDAPP1 ;
B lymphocyte adapter protein Bam32 ;
B-cell adapter molecule of 32 kDa
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背景:
function:May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR) -signaling downstream of PI3K. ,induction:Upon B-cell activation. ,PTM:Phosphorylated on tyrosine residues. ,similarity:Contains 1 PH domain. ,similarity:Contains 1 SH2 domain. ,subcellular location:Membrane-associated after cell stimulation leading to its translocation. ,subunit:Interacts with PtdIns (3 ,4 ,5) P3 and PLCG2. In vitro , interacts with PtdIns (3 ,4) P2. ,tissue specificity:Highly expressed in placenta and lung , followed by brain , heart , kidney , liver , pancreas and skeletal muscle. Expressed by B-lymphocytes , but not T-lymphocytes or nonhematopoietic cells. ,
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功能:
Function:May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR) -signaling downstream of PI3K. ,induction:Upon B-cell activation. ,PTM:Phosphorylated on tyrosine residues. ,similarity:Contains 1 PH domain. ,similarity:Contains 1 SH2 domain. ,subcellular location:Membrane-associated after cell stimulation leading to its translocation. ,subunit:Interacts with PtdIns (3 ,4 ,5) P3 and PLCG2. In vitro , interacts with PtdIns (3 ,4) P2. ,tissue specificity:Highly expressed in placenta and lung , followed by brain , heart , kidney , liver , pancreas and skeletal muscle. Expressed by B-lymphocytes , but not T-lymphocytes or nonhematopoietic cells. ,
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细胞定位:
Cytoplasm . Membrane ; Peripheral membrane protein . Membrane-associated after cell stimulation leading to its translocation.
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研究领域:
>>B cell receptor signaling pathway
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货号: YP0549
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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