CD31 (Phospho Tyr713) Rabbit pAb
-YP0530
主要信息
Target
CD31 Phospho Tyr713
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IHC, IF, ELISA
MW
150kD (Observed)
Conjugate/Modification
Phospho
货号: YP0530
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Phospho-CD31 (Y713) Polyclonal Antibody detects endogenous levels of CD31 protein only when phosphorylated at Y713.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):TVySE
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
实测条带
150kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human PECAM-1 around the phosphorylation site of Tyr713. AA range:686-735
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特异性:
Phospho-CD31 (Y713) Polyclonal Antibody detects endogenous levels of CD31 protein only when phosphorylated at Y713.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):TVySE
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基因名称:
PECAM1
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蛋白名称:
Platelet endothelial cell adhesion molecule
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别名:
PECAM1 ;
Platelet endothelial cell adhesion molecule ;
PECAM-1 ;
EndoCAM ;
GPIIA' ;
PECA1 ;
CD antigen CD31
Platelet endothelial cell adhesion molecule ;
PECAM-1 ;
EndoCAM ;
GPIIA' ;
PECA1 ;
CD antigen CD31
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背景:
The protein encoded by this gene is found on the surface of platelets , monocytes , neutrophils , and some types of T-cells , and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration , angiogenesis , and integrin activation. [provided by RefSeq , May 2010] ,
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功能:
Function:This protein is a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. ,online information:CD31 entry ,online information:PECAM-1 ,online information:The Singapore human mutation and polymorphism database ,PTM:Phosphorylated on Ser and Tyr residues after cellular activation. ,similarity:Contains 6 Ig-like C2-type (immunoglobulin-like) domains. ,tissue specificity:Long isoform predominates all tissues examined , isoform Delta12 was detected only in trachea and isoform Delta14-15 only in lung , isoform Delta14 was detected in all tissues examined with the strongest expression in heart. ,
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细胞定位:
Cell membrane ; Single-pass type I membrane protein . Cell surface expression on neutrophils is down-regulated upon fMLP or CXCL8/IL8-mediated stimulation. .; [Isoform Long]: Cell membrane ; Single-pass type I membrane protein . Membrane raft . Cell junction . Localizes to the lateral border recycling compartment (LBRC) and recycles from the LBRC to the junction in resting endothelial cells. .; [Isoform Delta15]: Cell junction . Localizes to the lateral border recycling compartment (LBRC) and recycles from the LBRC to the junction in resting endothelial cells.
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研究领域:
>>Cell adhesion molecules ;
>>Leukocyte transendothelial migration ;
>>Malaria ;
>>Fluid shear stress and atherosclerosis
>>Leukocyte transendothelial migration ;
>>Malaria ;
>>Fluid shear stress and atherosclerosis
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信号通路
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货号: YP0530
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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