Ron (Phospho Ser1394) Rabbit pAb
-YP0346
主要信息
Target
Ron Phospho Ser1394
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IHC, ELISA
MW
152kD (Observed)
Conjugate/Modification
Phospho
货号: YP0346
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; IHC 1:50-300; ELISA :5000-1:20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Phospho-Ron (S1394) Polyclonal Antibody detects endogenous levels of Ron protein only when phosphorylated at S1394.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):PLsEP
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
实测条带
152kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human CD136/RON around the phosphorylation site of Ser1394. AA range:1351-1400
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特异性:
Phospho-Ron (S1394) Polyclonal Antibody detects endogenous levels of Ron protein only when phosphorylated at S1394.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):PLsEP
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基因名称:
MST1R
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蛋白名称:
Macrophage-stimulating protein receptor
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别名:
MST1R ;
PTK8 ;
RON ;
Macrophage-stimulating protein receptor ;
MSP receptor ;
CDw136 ;
Protein-tyrosine kinase 8 ;
p185-Ron ;
CD antigen CD136
PTK8 ;
RON ;
Macrophage-stimulating protein receptor ;
MSP receptor ;
CDw136 ;
Protein-tyrosine kinase 8 ;
p185-Ron ;
CD antigen CD136
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背景:
This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits , generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung , and together with MSP , thought to be involved in host defense. Alternative splicing generates multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq , Jan 2016] ,
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功能:
Catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. ,Function:Receptor for macrophage stimulating protein (MSP) . Has a tyrosine-protein kinase activity. ,PTM:Phosphorylated in response to ligand binding. ,PTM:Proteolytic processing yields the two subunits. ,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. ,similarity:Contains 1 protein kinase domain. ,similarity:Contains 1 Sema domain. ,similarity:Contains 3 IPT/TIG domains. ,subunit:Heterodimer formed of an alpha chain and a beta chain which are disulfide linked. Binds PLXNB1. Associates with and is negatively regulated by HYAL2. ,tissue specificity:Keratinocytes and lung. ,
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细胞定位:
Membrane; Single-pass type I membrane protein.
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研究领域:
>>Calcium signaling pathway
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货号: YP0346
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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