MyoD (Phospho Ser200) Rabbit pAb
-YP0312
主要信息
Target
MyoD1 Phospho Ser200
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
34kD (Observed)
Conjugate/Modification
Phospho
货号: YP0312
规格
价格
货期
数量
200μL
￥4,680.00
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0
100μL
￥2,800.00
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0
50μL
￥1,500.00
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0
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详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Phospho-MyoD (S200) Polyclonal Antibody detects endogenous levels of MyoD protein only when phosphorylated at S200.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):ASsPR
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
实测条带
34kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human MYOD around the phosphorylation site of Ser200. AA range:171-220
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特异性:
Phospho-MyoD (S200) Polyclonal Antibody detects endogenous levels of MyoD protein only when phosphorylated at S200.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):ASsPR
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基因名称:
MYOD1;BHLHC1;MYF3;MYOD
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蛋白名称:
Myoblast determination protein 1
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别名:
MYOD1 ;
BHLHC1 ;
MYF3 ;
MYOD ;
Myoblast determination protein 1 ;
Class C basic helix-loop-helix protein 1 ;
bHLHc1 ;
Myogenic factor 3 ;
Myf-3
BHLHC1 ;
MYF3 ;
MYOD ;
Myoblast determination protein 1 ;
Class C basic helix-loop-helix protein 1 ;
bHLHc1 ;
Myogenic factor 3 ;
Myf-3
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背景:
This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest , a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis. [provided by RefSeq , Jul 2008] ,
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功能:
Function:Involved in muscle differentiation (myogenic factor) . Induces fibroblasts to differentiate into myoblasts. Activates muscle-specific promoters. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins. ,online information:MyoD entry ,PTM:Acetylated by a complex containing EP300 and PCAF. The acetylation is essential to activate target genes. Conversely , its deacetylation by SIRT1 inhibits its function. ,PTM:Ubiquitinated on the N-terminus; which is required for proteasomal degradation. ,similarity:Contains 1 basic helix-loop-helix (bHLH) domain. ,subunit:Efficient DNA binding requires dimerization with another bHLH protein. Seems to form active heterodimers with ITF-2. Interacts with SUV39H1. ,
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细胞定位:
Nucleus.
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组织表达:
研究领域:
>>Spinocerebellar ataxia
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货号: YP0312
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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