VE-Cadherin (Phospho Tyr731) Rabbit pAb
-YP0808
主要信息
Target
VE-Cadherin Phospho Tyr731
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IHC, IF, ELISA
MW
130kD (Observed)
Conjugate/Modification
phosphate
货号: YP0808
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Phospho-VE-Cadherin (Y731) Polyclonal Antibody detects endogenous levels of VE-Cadherin protein only when phosphorylated at Y731.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):HIyGY
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
实测条带
130kD
修饰
phosphate
克隆性
Polyclonal
同种型
IgG
相关产品
Primary Antibodies
VE-Cadherin Rabbit pAb
YT6128
预览→
Primary Antibodies
VE-Cadherin Rabbit pAb
YT5611
预览→
Primary Antibodies
VE-Cadherin Rabbit pAb
YT4869
预览→
Primary Antibodies
VE-Cadherin (Phospho Tyr731) Rabbit pAb
YP0808
预览→
Primary Antibodies
VE-Cadherin (3G8) Mouse mAb
YM3762
预览→
ELISA Kits
Total VE-Cadherin Cell-Based Colorimetric ELISA Kit
KA4320C
预览→
抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human VE-Cadherin around the phosphorylation site of Tyr731. AA range:697-746
展开内容
特异性:
Phospho-VE-Cadherin (Y731) Polyclonal Antibody detects endogenous levels of VE-Cadherin protein only when phosphorylated at Y731.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):HIyGY
展开内容
基因名称:
CDH5
展开内容
蛋白名称:
Cadherin-5
展开内容
别名:
CDH5 ;
Cadherin-5 ;
7B4 antigen ;
Vascular endothelial cadherin ;
VE-cadherin ;
CD antigen CD144
Cadherin-5 ;
7B4 antigen ;
Vascular endothelial cadherin ;
VE-cadherin ;
CD antigen CD144
展开内容
背景:
This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats , a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner , this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. [provided by RefSeq , Nov 2015] ,
展开内容
功能:
Function:Cadherins are calcium dependent cell adhesion proteins. ,Function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. ,similarity:Contains 5 cadherin domains. ,subcellular location:Found at cell-cell boundaries and probably at cell-matrix boundaries. ,tissue specificity:Endothelial tissues and brain. ,
展开内容
细胞定位:
Cell junction . Cell membrane ; Single-pass type I membrane protein . Found at cell-cell boundaries and probably at cell-matrix boundaries. KRIT1 and CDH5 reciprocally regulate their localization to endothelial cell-cell junctions. .
展开内容
组织表达:
研究领域:
>>Cell adhesion molecules ;
>>Leukocyte transendothelial migration ;
>>Fluid shear stress and atherosclerosis
>>Leukocyte transendothelial migration ;
>>Fluid shear stress and atherosclerosis
展开内容
信号通路
文献引用（{{totalcount}}）
货号: YP0808
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
Recently Viewed Products
Clear all
×
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
主要信息
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
产品 {{index}}/{{pcount}}
上一个产品
下一个产品
{{pvTitle}}
滚轮缩放图片
{{pvDescr}}