GSK3α (Phospho Ser21) Rabbit pAb
-YP0122
主要信息
Target
GSK3α Phospho Ser21
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, IP, ELISA
MW
55kD (Observed)
Conjugate/Modification
Phospho
货号: YP0122
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; IP 2-5 ug/mg lysate; ELISA 1:20000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Phospho-GSK3α (S21) Polyclonal Antibody detects endogenous levels of GSK3α protein only when phosphorylated at S21.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):TSsFA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
实测条带
55kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human GSK3 alpha around the phosphorylation site of Ser21. AA range:10-59
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特异性:
Phospho-GSK3α (S21) Polyclonal Antibody detects endogenous levels of GSK3α protein only when phosphorylated at S21.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):TSsFA
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基因名称:
GSK3A
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蛋白名称:
Glycogen synthase kinase-3 alpha
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别名:
GSK3A ;
Glycogen synthase kinase-3 alpha ;
GSK-3 alpha ;
Serine/threonine-protein kinase GSK3A
Glycogen synthase kinase-3 alpha ;
GSK-3 alpha ;
Serine/threonine-protein kinase GSK3A
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背景:
glycogen synthase kinase 3 alpha (GSK3A) Homo sapiens This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase , and transcription factors , such as JUN. It also plays a role in the WNT and PI3K signaling pathways , as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. [provided by RefSeq , Oct 2011] ,
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功能:
Catalytic activity:ATP + [tau protein] = ADP + [tau protein] phosphate. ,Function:Implicated in the hormonal control of several regulatory proteins including glycogen synthase , MYB and the transcription factor JUN. ,similarity:Belongs to the protein kinase superfamily. ,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily. ,similarity:Contains 1 protein kinase domain. ,subunit:Monomer. ,
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细胞定位:
apical dendrite;axon;beta-catenin destruction complex;cytoplasm;cytosol;mitochondrion;neuronal cell body;nucleus;postsynapse;proximal dendrite;
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研究领域:
>>Chemokine signaling pathway ;
>>Dopaminergic synapse ;
>>Non-alcoholic fatty liver disease ;
>>Shigellosis
>>Dopaminergic synapse ;
>>Non-alcoholic fatty liver disease ;
>>Shigellosis
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信号通路
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货号: YP0122
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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