Rab 5A Rabbit pAb
-YT5456
主要信息
Target
Rab 5A
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
24kD (Observed)
Conjugate/Modification
Unmodified
货号: YT5456
规格
价格
货期
数量
200μL
￥3,780.00
一个月
0
100μL
￥2,300.00
一个月
0
40μL
￥960.00
一个月
0
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详细信息
推荐稀释比
WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:20000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Rab 5A Polyclonal Antibody detects endogenous levels of Rab 5A protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
实测条带
24kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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RS0001
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RS0002
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β-actin (PTR2364) Mouse mAb
YM3028
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GAPDH (PTR2304) Mouse mAb
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from the Internal region of human RAB5A. AA range:71-120
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特异性:
Rab 5A Polyclonal Antibody detects endogenous levels of Rab 5A protein.
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基因名称:
RAB5A
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蛋白名称:
Ras-related protein Rab-5A
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别名:
RAB5A ;
RAB5 ;
Ras-related protein Rab-5A
RAB5 ;
Ras-related protein Rab-5A
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背景:
enzyme regulation:Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP. ,function:Required for the fusion of plasma membranes and early endosomes. ,similarity:Belongs to the small GTPase superfamily. Rab family. ,subcellular location:Enriched in stage I melanosomes. ,subunit:Binds EEA1. Interacts with RIN1 and GAPVD1 , which regulate its pathway , probably by acting as a GEF. Interacts with ALS2CL , UNC84B , ZFYVE20 and RUFY1. Interacts with SGSM1 and SGSM3. ,
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功能:
enzyme regulation:Regulated by guanine nucleotide exchange factors (GEFs) which promote the exchange of bound GDP for free GTP. ,Function:Required for the fusion of plasma membranes and early endosomes. ,similarity:Belongs to the small GTPase superfamily. Rab family. ,subcellular location:Enriched in stage I melanosomes. ,subunit:Binds EEA1. Interacts with RIN1 and GAPVD1 , which regulate its pathway , probably by acting as a GEF. Interacts with ALS2CL , UNC84B , ZFYVE20 and RUFY1. Interacts with SGSM1 and SGSM3. ,
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细胞定位:
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Early endosome membrane ; Lipid-anchor . Melanosome . Cytoplasmic vesicle . Cell projection , ruffle . Membrane . Cytoplasm , cytosol . Cytoplasmic vesicle , phagosome membrane . Endosome membrane . Enriched in stage I melanosomes (PubMed:17081065) . Alternates between membrane-bound and cytosolic forms (Probable) . .
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组织表达:
研究领域:
>>Ras signaling pathway ;
>>Endocytosis ;
>>Phagosome ;
>>Vasopressin-regulated water reabsorption ;
>>Amyotrophic lateral sclerosis ;
>>Pathways of neurodegeneration - multiple diseases ;
>>Salmonella infection ;
>>Amoebiasis ;
>>Tuberculosis
>>Endocytosis ;
>>Phagosome ;
>>Vasopressin-regulated water reabsorption ;
>>Amyotrophic lateral sclerosis ;
>>Pathways of neurodegeneration - multiple diseases ;
>>Salmonella infection ;
>>Amoebiasis ;
>>Tuberculosis
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信号通路
Cellular Processes >> Transport and catabolism >> Phagosome
Cellular Processes >> Transport and catabolism >> Mitophagy - animal
Human Diseases >> Neurodegenerative disease >> Amyotrophic lateral sclerosis
Human Diseases >> Neurodegenerative disease >> Pathways of neurodegeneration - multiple diseases
Environmental Information Processing >> Signal transduction >> Ras signaling pathway
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货号: YT5456
规格
价格
货期
数量
200μL
￥3,780.00
一个月
0
100μL
￥2,300.00
一个月
0
40μL
￥960.00
一个月
0
加入购物车
已收藏
收藏
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