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ELP3 Rabbit pAb

-YN0697

2 5
主要信息
Target

ELP3

Host Species

Rabbit

Reactivity

Human, Mouse

Applications

WB, ELISA

MW

60kD (Observed)

Conjugate/Modification

Unmodified

货号: YN0697
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

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详细信息
推荐稀释比
WB 1:500-2000; ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
ELP3 Polyclonal Antibody detects endogenous levels of protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
实测条带
60kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from part region of human protein. AA range:21-121
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特异性:
ELP3 Polyclonal Antibody detects endogenous levels of protein.
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基因名称:
ELP3
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蛋白名称:
Elongator complex protein 3 (hELP3) (EC 2.3.1.48)
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数据库链接:
Organism 基因 ID SwissProt
Human 55140; Q9H9T3;
Mouse Q9CZX0;
背景:
ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex , which contributes to transcript elongation and also regulates the maturation of projection neurons (Creppe et al. , 2009 [PubMed 19185337]) .[supplied by OMIM , Apr 2009] ,
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功能:
Catalytic activity:Acetyl-CoA + histone = CoA + acetylhistone. ,cofactor:Binds 1 4Fe-4S cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. ,Function:Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex , which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. May also have a methyltransferase activity. ,similarity:Belongs to the ELP3 family. ,similarity:Contains 1 N-acetyltransferase domain. ,subunit:Component of the RNA polymerase II elongator complex (Elongator) , which consists of IKBKAP/ELP1 , STIP1/ELP2 , ELP3 , ELP4 , and two yet unidentified proteins , p30 and p38. IKBKAP/ELP1 , STIP1/ELP2 and ELP3 form the Elongator core complex. Elongator associates with the C-terminal domain (CTD) of Pol II largest subunit. Interacts with IKBKAP/ELP1. ,
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细胞定位:
Cytoplasm . Nucleus .; [Isoform 1]: Nucleus .; [Isoform 2]: Cytoplasm . Nucleus .
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货号: YN0697
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询
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