Purified Mouse Anti Human CD64 Antibody (PTF0068)
-YF0068
主要信息
Target
CD64
Host Species
Mouse
Reactivity
Human
Applications
IF, FC
Conjugate/Modification
Unmodified
详细信息
推荐稀释比
IF 1:200-1:1000; FC:1 µg per million cells in 100 µl volume. For optimal results, the reagent should be titrated according to each specific application
组成
PBS, pH 7.4
特异性
Endogenous
纯化工艺
Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
储存
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
修饰
Unmodified
克隆性
Monoclonal
克隆号
PTF0068
同种型
Mouse IgG1/Kappa
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
预览→
Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
预览→
Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
预览→
Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029
预览→
抗原&靶点信息
免疫原:
The specific immunogen used to produce this antibody is proprietary information.
展开内容
特异性:
Endogenous
展开内容
基因名称:
FCGR1A FCG1 FCGR1 IGFR1
展开内容
蛋白名称:
High affinity immunoglobulin gamma Fc receptor I (IgG Fc receptor I) (Fc-gamma RI) (FcRI) (Fc-gamma RIA) (FcgammaRIa) (CD antigen CD64)
展开内容
别名:
High affinity immunoglobulin gamma Fc receptor I ;
IgG Fc receptor I ;
Fc-gamma RI ;
FcRI ;
Fc-gamma RIA ;
FcgammaRIa ;
CD antigen CD64 ;
IgG Fc receptor I ;
Fc-gamma RI ;
FcRI ;
Fc-gamma RIA ;
FcgammaRIa ;
CD antigen CD64 ;
展开内容
背景:
This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq , Jul 2008] ,
展开内容
功能:
Function:High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. ,online information:FCGR1A mutation db ,PTM:N-glycosylated. ,PTM:Phosphorylated on serine residues. ,similarity:Belongs to the immunoglobulin superfamily. FCGR1 family. ,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains. ,subcellular location:Stabilized at the cell membrane through interaction with FCER1G. ,subunit:Interacts with FCERG1; forms a functional signaling complex. Interacts with FLNA; prevents FCGR1A degradation. Interacts with EPB41L2 , LAT and PPL. ,tissue specificity:Monocyte/macrophage specific. ,
展开内容
细胞定位:
Cell membrane ; Single-pass type I membrane protein . Stabilized at the cell membrane through interaction with FCER1G.
展开内容
组织表达:
研究领域:
>>Phagosome ;
>>Osteoclast differentiation ;
>>Neutrophil extracellular trap formation ;
>>Hematopoietic cell lineage ;
>>Fc gamma R-mediated phagocytosis ;
>>Leishmaniasis ;
>>Staphylococcus aureus infection ;
>>Tuberculosis ;
>>Transcriptional misregulation in cancer ;
>>Acute myeloid leukemia ;
>>Systemic lupus erythematosus
>>Osteoclast differentiation ;
>>Neutrophil extracellular trap formation ;
>>Hematopoietic cell lineage ;
>>Fc gamma R-mediated phagocytosis ;
>>Leishmaniasis ;
>>Staphylococcus aureus infection ;
>>Tuberculosis ;
>>Transcriptional misregulation in cancer ;
>>Acute myeloid leukemia ;
>>Systemic lupus erythematosus
展开内容
信号通路
Cellular Processes >> Transport and catabolism >> Phagosome
Organismal Systems >> Immune system >> Hematopoietic cell lineage
Organismal Systems >> Immune system >> Neutrophil extracellular trap formation
Organismal Systems >> Immune system >> Fc gamma R-mediated phagocytosis
Organismal Systems >> Development and regeneration >> Osteoclast differentiation
Human Diseases >> Cancer: overview >> Transcriptional misregulation in cancer
Human Diseases >> Cancer: specific types >> Acute myeloid leukemia
Human Diseases >> Immune disease >> Systemic lupus erythematosus
文献引用（{{totalcount}}）
Recently Viewed Products
Clear all
×
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
主要信息
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
产品 {{index}}/{{pcount}}
上一个产品
下一个产品
{{pvTitle}}
滚轮缩放图片
{{pvDescr}}