Synthesized peptide derived from human QCR1 AA range: 164-214

This antibody detects endogenous levels of QCR1 at Human/Mouse/Rat

UQCRC1

QCR1

Caution:Does not seem to have a protease activity as it lack the zinc-binding site. ,Function:This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) , which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. ,similarity:Belongs to the peptidase M16 family. UQCRC1/QCR1 subfamily. ,subunit:The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b , cytochrome c1 and Rieske/UQCRFS1) , 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6 , UQCRB/QCR7 , UQCRQ/QCR8 , UQCR10/QCR9 , UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1) . ,

Mitochondrion inner membrane ; Peripheral membrane protein ; Matrix side .

>>Oxidative phosphorylation ;
>>Metabolic pathways ;
>>Cardiac muscle contraction ;
>>Thermogenesis ;
>>Non-alcoholic fatty liver disease ;
>>Alzheimer disease ;
>>Parkinson disease ;
>>Amyotrophic lateral sclerosis ;
>>Huntington disease ;
>>Prion disease ;
>>Pathways of neurodegeneration - multiple diseases ;
>>Chemical carcinogenesis - reactive oxygen species ;
>>Diabetic cardiomyopathy